SPACELINE The current recognition list is distributed via listserv and available from the NASA Task Book website. https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please address your correspondence to her SPACELINE Current Affairs Senior Editor, Shawna Byrd. [email protected].
We are looking for articles to cite for our weekly list. Authors at NASA Centers and NASA PIs — Do you have any papers in the space life sciences that have been recently published or will be published in the coming weeks in peer-reviewed journals? If so, send it our way! Please send your article to the email address above. Articles received by Wednesday will appear in that week’s list. Articles received after Wednesday will appear the following week.
Papers derived from NASA support:
1
Lonner TL, Allred AR, Bonarrigo L, Gopinath A, Smith K, Kravetz V, Groen EL, Oman C, DiGio P, Lawson BD, Clark TK.
Virtual reality as a measure against motion sickness for astronauts during post-flight water landing simulations.
Exp Brain Res. October 5, 2023.
https://pubmed.ncbi.nlm.nih.gov/37796301
PI: TK Clark
Note: From the abstract: “After prolonged adaptation to microgravity, crew members returning to Earth are affected by motion sickness (EMS). Anticholinergic drugs (such as meclizine) are often taken before landing. However, there are adverse operational side effects (such as drowsiness). Non-pharmaceutical EMS countermeasures also need to be developed. We evaluate the effectiveness of technical countermeasures that provide external visual cues after splashdown. Otherwise, only visual references in the nauseous cabin are available. Our measure provides visual cues for the motion congruence of the earth-fixed scene in virtual reality, and each It was compared to a control condition with fixation points fixed on the head in virtual reality in a between-subjects design with 15 subjects in a group. We tested the effectiveness of the measures to reduce motion sickness symptoms at the end of a 2Gx centrifugation followed by up to 1 hour of undulating exercise.”
Journal impact factor: 2.0
Funding: “This research was supported by the National Aeronautics and Space Administration Human Research Program under grant number 80NSSC21K0257. Additionally, this research was supported by a NASA Space Technology Graduate Research Opportunity Award.”
2
Elder CA, Moore J, Janis BR, Shacklett S, Jones C, Cantrell R, Grimm DF, Pantalos G, Kopeczek JA, Menze MA.
Rehydration results of freeze-dried red blood cells under reduced gravity.
Acta astronaut. 2023 10 10. Online before printing.
https://doi.org/10.1016/j.actastro.2023.10.006
Note: From the abstract: “This study investigates whether red blood cells are freeze-dried. [red blood cells] Hydration and blood transfusions are possible in reduced gravity, with recovery outcomes similar to those observed in Earth’s gravity. ”
Journal impact factor: 3.5
Funding: “This research was supported by NASA Award Number: 80NSSC18K1664 and NASA Award Number: NNX15AR69H.”
3
Poplaski V, Sawyer FM, Bluett SE.
Small intestine microbiome: symbiotic with intestinal stem cells.
Microbiota and host. 2023 10 1. Online before printing.
https://doi.org/10.1530/MAH-23-0012
PI: SE Bluet
Note: From the summary. “This review focuses on studies investigating interactions between ISCs. [intestinal stem cells] To elaborate on our current understanding of the microbial control of ISCs, we describe the small intestine microbiome. The results of these studies provide important knowledge that can be leveraged to identify therapeutic targets and develop new preventive treatments to treat intestinal diseases. ” This article is available for free online.
Journal impact factor: Not available for this journal
Funding: “This research was supported by National Institutes of Health grants U01-DK103168 and U19-AI116497 and Space Health Translational Institute grant NNX16AO69A.”
Four
Smith LT, Walsh RFL, Goel N, Alloy LB.
Trajectories of social jet lag and mood symptoms and reward reactivity in individuals with low-risk, high-risk, and bipolar spectrum disorders: An ecological momentary assessment study.
Psychiatric research. 2023 Nov;329:115499.
https://doi.org/10.1016/j.psychres.2023.115499
PI: N. Goel
Journal impact factor: 11.3
Funding: “Namni Goel was supported in part by National Aeronautics and Space Administration (NASA) grants NNX14AN49G and 80NSSC20K0243 and National Institutes of Health grant R01DK117488.…”
Five
Coulombe JC, Maridas DE, Chou JL, Bousain ML.
small animal DXA [dual-energy X-ray absorptiometry] Equipment comparison and validation.
Bone. 2023 9 29;116923. Online ahead of print.
https://doi.org/10.1016/j.bone.2023.116923
PI: ML Busein
Journal impact factor: 4.1
Funding: “This research was funded by NASA Human Research Program grant 80NSSC19K0534.…”
6
Trovao NS, Pan V, Goel C, Gallego-Garcia P, Liu Y, Barbara C, Borg R, Brifa M, Cilia C, Gretsch L, Vassallo M, Treangen TJ, Posada D, Beheshti A, Borg J, Zahra G.
Evolutionary and spatiotemporal analyzes revealed multiple introductions and cryptic transmission of SARS-CoV-2 VOC/VOIs in Malta.
Microbial spectrum. 2023 10 6;e0153923. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/37800925
Note: This article is available for free online.
Journal impact factor: 9.0
Funding: A. Beheshti is with the NASA Ames Research Center.
_______________________________________________
Other interesting papers:
1
Blaber AP, Sadeghian F, Naz Divsalar D, Scarisbrick IA.
Elevated biomarkers of neurological injury in older adults after head-down bed rest: association between spaceflight and age-related declines in cardiac and postural conditions.
Front ham neurosti. 2023 9 26;17:1208273.
https://doi.org/10.3389/fnhum.2023.1208273
Note: A study of bedrests with head tilted downwards. This article is part of the research topic “Brains in space: The effects of spaceflight on the human brain and behavior – Volume II” (https://www.frontiersin.org/research-topics/47491/brains-in-space-Effects-of-spaceflight-on-the-human-brain-and-behavior—volume-ii#overview).Research topics also include previous Latest Awareness List #1,041 articles https://doi.org/10.3389/fphys.2023.1141078; #1,046 https://doi.org/10.3389/fncir.2023.1135434; #1,051 https://doi.org/10.3389/fphys.2023.1146096; #1,053 https://doi.org/10.3389/fphys.2023.1141015; #1,056 https://doi.org/10.3389/fnins.2023.1180314; #1,059 https://doi.org/10.3389/fncir.2023.1190582 and https://doi.org/10.3389/fncir.2023.1197278; #1,061 https://doi.org/10.3389/fphys.2023.1201253; and #1,062 https://doi.org/10.3389/fncir.2023.1170395. This article is available for free online.
2
Smith L.
Space station and spacecraft environmental conditions and human mental health: specific recommendations and guidelines.
Life Science and Space Research Institute 2023 10 11. Online before printing.
https://doi.org/10.1016/j.lssr.2023.10.001
Note: From the abstract: “This manuscript briefly reviews what is known about the main components of space habitats (e.g., noise levels, lighting, air quality, privacy, plant growth, etc.) and provides specific and clear It is intended to provide recommendations for mission planners and space habitat designers. Where appropriate, future research opportunities are highlighted.”
3
White New Jersey, Wente A.
Hemostasis management in space.
Atherosclerotic thrombus Vasc Biol. 2023 10 5. Review. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/37795614
Note: From the abstract: “Human space travel requires exposure to weightlessness, ionizing radiation, isolation, and austerity. A recent report on internal jugular vein thrombosis in astronauts in low Earth orbit It has been established that exposure also affects vascular biology, affecting thrombosis and hemostasis diseases. This brief review examines the known effects of space travel on inflammation, blood coagulation, and the cardiovascular system. We summarize and conceptualize how they work together to influence thrombosis and hemostasis.”
Four
Pagliarello R, Benici E, Di Sarcina I, Villani ME, Desiderio A, Nardi L, Benvenuto E, Cemi A, Massa S.
Effects of gamma rays on biofortified genetically engineered tomatoes for space agriculture using morphometric and fluorescence-based indicators.
Front Plant Science 2023 10 9;14:1266199.
https://doi.org/10.3389/fpls.2023.1266199
Note: This article is part of the research theme “Future advances in space agriculture” (https://www.frontiersin.org/research-topics/52433/progressing-the-future-of-space-agriculture#overview).Research topics also include previous Latest Awareness List #1,055 articles https://doi.org/10.3389/fpls.2023.1194753 and #1,069 https://doi.org/10.3389/fpls.2023.1265458. This article is available for free online.
Five
Miao LW, Liu TZ, Sun YH, Cai N, Xuan YY, Wei Z, Cui BB, Jing LL, Ma HP, Xian CJ, Wang JF, Gao YH, Chen KM.
Pseudo-microgravity-induced oxidative stress and loss of osteoblast osteogenic capacity can be prevented by protection of primary cilia.
J Cell Physiol. 2023 10 5. Online before printing.
https://pubmed.ncbi.nlm.nih.gov/37796139
Note: A random positioning machine was used in this study.
6
Zhou Y, Lv W, Peng X, Cheng Y, Tu Y, Song G, Luo Q.
Pseudo-microgravity attenuates dermal wound healing by inhibiting dermal fibroblast migration via the F-actin/YAP signaling pathway.
J Cell Physiol. 2023 10 5. Online before printing.
https://pubmed.ncbi.nlm.nih.gov/37795566
Note: From the abstract: “The skin and its cellular components are constantly exposed to external and internal mechanical forces and are mechanically sensitive. Disturbances in mechanical homeostasis can lead to changes in skin function. Gravity is an essential mechanical force on Earth. However, little is known about how it contributes to maintaining skin function and how the microgravity of space affects wound healing. Here, we use a microgravity analog to show that simulated microgravity (SMG) inhibits dermal wound healing and dermal fibroblast accumulation in the wound bed.”
7
Cui X, Song W, Xue Y, Jing H, Lei M, Ma H, He X, Zou P, Wu B, Wang J.
Numerical analysis of minute moon dust deposition in human nasal airways.
J. Hazard Meter. 2024 Jan 5;461:132682.
https://pubmed.ncbi.nlm.nih.gov/37793250
8
Post TE, Hein LG, Jordan J, Van Gerven JMA.
Sensitivity of cognitive function tests to acute hypoxia in healthy subjects: A systematic literature review.
front physical. 2023 10 11;14:1244279.
https://doi.org/10.3389/fphys.2023.1244279
Note: This article is available for free online.
9
Kang JH, Lee HY, Kim NY, Lee DS, Im M.
Extracellular Prdx1 mediates bacterial infections and inflammatory bone diseases.
Life science. 2023 11 15;333:122140.
https://pubmed.ncbi.nlm.nih.gov/37797684
Ten
Kasenave L, Einenkel M, Yurkevich A, Endo S, Hirsch S, Bourdet E.
Hybrid robotic and electrical stimulation assistance can improve performance and reduce mental demands.
IEEE Transneural Systems Rehabilitation Engineering 2023 10 10. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/37815973
Note: This article is available for free online.
11
Luiken MC, Appenzeller P, Scheiwiller PM, Lichtblau M, Mademirov M, Muratbekova A, Shelaliev U, Abdullaeva A, Marazhapov N, Solonbaev TM, Ulrich S, Bloch KE, Furian M.
Time course of cerebral oxygenation and cerebrovascular reactivity in highland residents of Kyrgyzstan. A 5-year prospective cohort study.
front physical. 2023 10 10;14.
https://doi.org/10.3389/fphys.2023.1160050
Note: This article is part of the research theme “Neurological dysfunction and disease at high altitudes” (https://www.frontiersin.org/research-topics/48777/neurological-dysfunction-and-diseases-in-high-altitude#overview).Research topics also include previous Latest Awareness List #1,037 articles https://doi.org/10.3389/fphys.2023.1133059 and #1,065 https://doi.org/10.3389/fphys.2023.1191058. This article is available for free online.
12
Modi AD, Parekh A, Patel ZH.
A method to assess dynamic balance and coordination related to locomotion in rodents.
Behavioral Brain Research Institute 2024 January 5;456:114695. review.
https://pubmed.ncbi.nlm.nih.gov/37783346